郝立凯
姓名：郝立凯性别：男
职称：研究员
学位：博士，博士生导师
工作单位：中国科学院地球化学研究所环境地球化学国家重点实验室
地址：贵州省贵阳市观山湖区林城西路99号；550081
E-mail: haolikai@mail.gyig.ac.cn
简历：
2016-今 中国科学院地球化学研究所 研究员
2011-2015 德国埃贝哈德?卡尔斯图宾根大学 导师：马汀?欧博斯特教授 安德烈亚斯?开普勒教授
2007-2010 厦门大学 显微镜工程师 课题组长：焦念志教授 张锐教授
2004-2007山东大学 微生物学 硕士 导师：刘向梅教授 林建群教授
2000-2004 河北科技大学 生物技术 本科 导师：魏景芳教授
社会任职：
欧洲地球化学会会员
中国矿物岩石地球化学学会会员
中国化学会会员
中国旅德学者化学化工学会会员
研究方向：
1重金属微生物地球化学原位微观控制机制
2典型多金属采选场地土壤重金属污染物特征与控制机制
3高级光电联用环境分析显微镜技术
承担科研项目情况：
1 国家重点研发计划--典型多金属采选场地及周边土壤污染物源—汇关系及防治技术原理（2018YFC1802601），427万元
2 国家自然科学基金--微生物铁循环对原位微观重金属吸附的控制机制(41877400),61.00万元
3 大洋十三五项目印度洋靶区多金属硫化物资源综合评价与勘探区块圈定--矿物原位立体微观成像分析研究，25万元
4 环境地球化学国家重点实验室开放课题--一万五千年青藏高原兹格塘错湖泊沉积物微生物组结构和功能研究，10万元
代表论著：
1.Likai Hao, Yuan Guo, James M. Byrne, Fabian Zeitvogel, Gregor Schmid, Pablo Ingino, Jianli Li, Thomas R. Neu, Elizabeth Swanner, Andreas Kappler, Martin Obst (2016). Binding of heavy metal ions in aggregates of microbial cells, EPS and biogenic iron minerals measured in-situ using metal- and glycoconjugates-specific fluorophores. Geochimica et Cosmochimica Acta, 180, 66-96.
2.Likai Hao, Jianli Li, Andreas Kappler, Martin Obst (2013). Mapping of heavy metal ion sorption to cell-extracellular polymeric substance-mineral aggregates by using, metal-selective fluorescent probes and confocal laser scanning microscopy. Applied and Environmental Microbiology 79(21), 6524-6534.
3.Likai Hao, Xiangmei Liu, Huiyan Wang, Jianqun Lin, Xin Pang, Jianqiang Lin (2012). Detection and validation of a small broad-host-range plasmid pBBR1MCS-2 for use in genetic manipulation of the extremely acidophilic Acidithiobacillus sp. Journal of Microbiological Methods 90(3): 309-314.
4.Zheng Yang, Likai Hao, Bing Yin, Mengyao She, Martin Obst, Andreas Kappler, Yifan Kang, Ping, Liu, Jianli Li, and Zhen Shi (2013). Six-membered spirocycle opening triggered fluorescent probe for visualizing Hg2+ in living cells and bacteria-EPS-mineral aggregates. Organic Letters 15(17): 4334-4337. Co-first author
5.Xilang Jin, Likai Hao, Mengyao She, Martin Obst, Andreas Kappler, Jianli Li, Zhen Shi (2015). Visualizing tributyltin (TBT) in bacterial aggregates by specific rhodamine-based fluorescent probes. Analytica Chimica Acta 853(0): 514-520. Co-first author
6.Gregor Schmid, Fabian Zeitvogel, Likai Hao, Pablo Ingino, Irini Adaktylou, Merle Eickhoff, Martin Obst (2016). Submicron-scale heterogeneities in Nickel sorption of various cell-mineral aggregates formed by Fe(II)-oxidizing bacteria. Environ. Sci. Technol., 50 (1), 114–125
7.Mengyao She, Zheng Yang, Likai Hao, Zhaohui Wang, Tianyou Luo, Martin Obst, Ping Liu, Yehua Shen, Shengyong Zhang, Jianli Li (2016). "A novel approach to study the structure-property relationships and applications in living systems of modular Cu2+ fluorescent probes." Scientific Reports 6: 28972
8.Gregor Schmid, Fabian Zeitvogel, Likai Hao, Pablo Ingino, Wolfgang Kuerner, James J Dynes, Chithra Karunakaran, Jian Wang, Yingshen Lu, Travis Ayers, Chuck Schietinger, Adam P Hitchcock, Martin Obst (2014). Synchrotron-based chemical nano-tomography of microbial cell-mineral aggregates in their natural, hydrated state. Microscopy and Microanalysis 20 (2): 531-536.
9.Gregor Schmid, Fabian Zeitvogel, Likai Hao, Pablo Ingino, Matthias Floetenmeyer, York-Dieter Stierhof, Birgit Schroeppel, Claus J. Burkhardt, Andreas Kappler, Martin Obst (2014). 3-D analysis of bacterial cell-(iron)mineral aggregates formed during Fe(II) oxidation by the nitrate-reducing Acidovorax sp. strain BoFeN1 using complementary microscopy tomography approaches. Geobiology 12 (4): 340–361.
10.Fuxian Wang, Shiling Zheng, Hao Qiu, Changqian Cao, Xu Tang, Likai Hao, Fanghua Liu (2017). Ferrihydrite reduction and vivianite biomineralization mediated by iron reducing bacterium Shewanella oneidensis MR-4. Acta Microbiologica Sinica 58(4): 573-583.
11.Swanner, Elizabeth; Bayer, Tim; Wu, Wenfang; Hao, Likai; Obst, Martin; Sundman, Anneli; Byrne, James; Michel, F. Marc; Kappler, Andreas; Schoenberg, Ronny (2017). Iron isotope fractionation during Fe(II) oxidation mediated by the oxygen-producing marine cyanobacterium Synechococcus PCC 7002. Environmental Science & Technology 51(9): 4897-4906.
12.Fabian Zeitvogel, Gregor Schmid, Likai Hao, Pablo Ingino, Martin Obst (2016). ScatterJ: An ImageJ plugin for the evaluation of analytical microscopy datasets. Journal of Microscopy: 261(2): 148-156.
13.Elizabeth Swanner, Wenfang Wu, Likai Hao, Martin Obst, Mak Saito and Andreas Kappler (2015). Physiology, Fe(II) oxidation, and Fe mineral formation by a marine planktonic cyanobacterium grown under ferruginous conditions. Frontiers in Earth Science 3: 60.
14.Wenfang Wu, Elizabeth D. Swanner, Likai Hao, Fabian Zeitvogel, Martin Obst, Yongxin Pan, Andreas Kappler (2014). Characterization of the physiology and cell-mineral interactions of the marine anoxygenic phototrophic Fe(II)-oxidizer Rhodovulum iodosum - implications for Precambrian Fe(II) oxidation. FEMS Microbiology Ecology 88 (3): 503–515.
15.Yingheng Fei, Jian Hua, Chengshuai Liu, Fangbai Li, Zhenke Zhu, Tangfu Xiao, Manjia Chen, Ting Gao, Zhiqi Wei, Likai Hao (2018). "Aqueous Fe(II)-Induced Phase Transformation of Ferrihydrite Coupled Adsorption/Immobilization of Rare Earth Elements." Minerals 8(8): 357.
